Plenary Session 4:COVID-19
Time (GMT+8) |
Topic | Speaker | Country / Region |
---|---|---|---|
10:10-10:40 | Challenges of emerging infectious diseases on tuberculosis prevention and care | Dr. Jae-Joon Yim | South Korea |
Time (GMT+8) |
Topic | Speaker | Country / Region |
10:40-11:10 | Prevalence, risk factor, and prognosis of long COVID: now and feature | Dr. Jia-Yih Feng | Taiwan |
Challenges of emerging infectious diseases on tuberculosis prevention and care
Abstract :
Emerging infectious diseases, including severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), influenza A (H1N1)pdm.09, and COVID-19, could significantly impact the control of tuberculosis (TB). The substantial global impact of the COVID-19 pandemic, with reported cases exceeding 770 million worldwide, highlights the profound effects of emerging infectious diseases on TB in terms of epidemiology, diagnosis, treatment, and prognosis. According to the World Health Organization (WHO), the number of newly diagnosed TB cases decreased from 7.1 million in 2019 to 5.8 million in 2020, marking an 18% decline back to 2012 levels. Additionally, there were substantial reductions (-15%) in the number of patients treated for drug-resistant TB and (-21%) for TB prevention in 2020, potentially attributed to COVID-19-related disruptions in access to TB diagnosis and treatment. Compounding the challenges, the clinical presentation of COVID-19 and TB often overlaps, and co-infection is not uncommon. Although the treatment for each disease remains standard, aside from potential drug-drug interactions, TB patients co-infected with COVID-19 exhibited higher rates of treatment failure, loss to follow-up, and in-hospital mortality. Moreover, pulmonary sequelae from both COVID-19 and TB may overlap, leading to prolonged respiratory symptoms. While the COVID-19 pandemic wanes, the reported global number of newly diagnosed TB patients surged to 7.5 million in 2022—the highest since WHO began global TB monitoring in 1995. This resurgence is attributed to the disruption of TB services during the pandemic. To prevent such setbacks in the future, there is a critical need to strengthen essential TB services and prepare effective strategies against emerging infectious diseases.
Jae-Joon Yim
South Korea
Prevalence, risk factor, and prognosis of long COVID: now and feature
Long COVID-19, also known as Post-Acute Sequelae of SARS-CoV-2 infection (PASC), represents a significant and evolving challenge in the landscape of global health. Characterized by persistent symptoms and health issues that continue for weeks or months after the acute phase of COVID-19 has resolved, long COVID affects patients regardless of the severity of their initial infection. Its impact is broad, affecting multiple organ systems, and has profound implications for individuals, healthcare systems, and societies.
The spectrum of symptoms associated with long COVID is diverse, including but not limited to chronic fatigue, shortness of breath, chest pain, cognitive disturbances often referred to as “brain fog,” joint pain, and neurological symptoms. It also encompasses psychological sequelae such as depression and anxiety, underscoring the mental health impact of the condition. Importantly, long COVID can occur even in individuals who experienced mild initial COVID-19 symptoms, making it a concern for a significant portion of the infected population.
The pathophysiology behind long COVID is not fully understood, but several hypotheses include persistent immune activation, residual organ damage, and microvascular injury. These ongoing symptoms not only reduce the quality of life but also have socio-economic implications, as they can affect an individual’s ability to return to work and perform daily activities.
The prevalence of long COVID has prompted new clinical guidelines and rehabilitation strategies, aiming to address the complex, multi-systemic nature of the condition. Healthcare providers are adapting to manage this new chronic condition, which often requires a multidisciplinary approach involving general practitioners, specialists, and allied health professionals. Research is ongoing to understand the long-term consequences of the infection and to identify effective treatments.
Jia-Yih Feng
Taiwan
Prof. Guy Marks
Australia
Prof. Kuo-Chin Kao
Taiwan